PHSC 2433 - Advanced Biopharmaceutics and Pharmacokinetics (3)

The purpose of this course is to enable student pharmacists to understand advanced pharmacokinetic concepts in order to apply appropriate drug dosing regimens in individual patients for specific drugs, disease states, or pharmacogenomics information. The first portion of this class will reintroduce student pharmacists to basic pharmacokinetic principles and the physiological and mathematical relationships that underlie drug clearance. Block One will focus on understanding renal clearance concepts and its application to potential drug interactions as well as designing individual dosage regimens for vancomycin and aminoglycosides. Block Two will focus on understanding hepatic clearance concepts and its application to potential drug interactions as well as designing individual dosage regimens for phenytoin. Finally, Block Three will provide a comprehensive overview of biotechnology and pharmacogenomics as it relates to their potential impact on drug therapy, drug delivery, drug disposition, and drug response for both small molecule and biotechnology-derived drug products. This course is critical to providing the foundation for subsequent Pharmacotherapy courses and the application of pharmacokinetics, pharmacodynamics, and pharmacogenomics in practice.